As the UK experiences a significant heatwave, the Medicines and Healthcare products Regulatory Agency (MHRA) has issued urgent advice to the public regarding the safe storage and handling of medicines. The guidance comes as temperatures across the country are forecast to remain high, with some areas potentially reaching 30°C or more, posing a risk to the efficacy and safety of various pharmaceutical products.
The MHRA emphasises that many medicines, including tablets, liquids, and creams, are sensitive to heat and direct sunlight. Exposure to high temperatures can degrade active ingredients, alter their chemical structure, or even lead to a loss of potency, rendering them less effective or potentially harmful. This is particularly critical for life-saving medications or those used to manage chronic conditions.
Among the key recommendations is the instruction to store medicines below 25°C, or as specified on the packaging. For many common medications, this means finding a cool, dry place away from windows or heat sources. The MHRA also strongly advises against leaving medicines in direct sunlight, in hot cars, or in conservatories, where temperatures can quickly exceed safe limits. Even short periods of exposure to extreme heat can have detrimental effects.
For individuals with medicines that require refrigeration, such as certain insulins or biological therapies, it is crucial to ensure they remain within the recommended temperature range, typically between 2°C and 8°C. The MHRA suggests using a cool bag with ice packs for transport, but warns against freezing medicines unless specifically instructed, as this can also damage their composition.
Furthermore, the agency advises anyone who suspects their medicine may have been compromised by heat to consult a pharmacist or their GP. They can provide guidance on whether the medicine is still safe to use and advise on obtaining replacement supplies if necessary. The public should not attempt to use medicines that appear discoloured, have changed consistency, or show any other signs of degradation.
The Met Office has issued yellow and amber heat warnings across large parts of England and Wales, with temperatures expected to peak mid-week. London and the South East could see highs of 31°C, while parts of the Midlands and Northern England may experience 28-29°C. Scotland and Northern Ireland are also set to see warm conditions, though generally cooler, with temperatures around 20-24°C, but the advice on medicine storage remains pertinent for all regions.
Source: Medicines and Healthcare products Regulatory Agency (MHRA), Met Office