Jurgen Klopp is making his return to the dugout, managing Germany for the first time in two years as the Nations League kicks off a new cycle for international football. His maiden match will be against the Netherlands, who are now led by Barcelona legend Xavi.
Other nations are also starting fresh, with Sebastien Pocognoli taking over as Scotland's coach and Roberto Mancini beginning his second tenure as Italy manager. The three weeks of Nations League action will also see numerous players aiming to prove their value in the post-World Cup landscape.
Among those to watch are Germany's Florian Wirtz, who has faced doubts about his form at Liverpool, and Portugal captain Cristiano Ronaldo, 41, who remains in the squad under new manager Jorge Jesus. England's Trent Alexander-Arnold is also back in contention as a right-back, with manager Thomas Tuchel confirming his role.
Scotland's Oli McBurnie has earned a recall to the squad, while Robbie Ure is one of five newcomers. Brighton's Charalampos Kostoulas, 19, is also set to feature for Greece, having started the season with three goals and two assists in six games.