A world-first clinical trial, led by Australian researchers, has found that a common cholesterol-lowering medication can reduce the risk of a heart attack or stroke for people aged over 70. The study also indicated a low risk of serious side effects.
Statins are currently prescribed to individuals under 75 who meet specific risk criteria, such as having diabetes and high cholesterol, to prevent major heart events. They are also given to patients who have already experienced a major heart event, regardless of age.
The trial, which involved nearly 10,000 participants over 70, aimed to determine if statins could safely prevent cardiac events in otherwise healthy older adults who had not previously had a heart attack, stroke, or heart surgery. The research found that the medication decreased the risk of a first major cardiovascular event by 30% for this age group.
While the study showed a reduction in major heart events, it also noted that disability-free survival was the same for both statin and placebo groups, meaning the medication did not extend life or its quality. Researchers hope the strong evidence will lead to updated treatment guidelines.