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Woman with HER2 gene mutation sees lung tumour shrink on trial drug

A 75-year-old woman from Greenwich, who has had four cancer diagnoses since the 1980s, is taking a daily tablet as part of a clinical trial for lung cancer.

  • Susan Gasson, 75, was diagnosed with lung cancer in October 2020, her fourth cancer diagnosis in four decades.
  • She has a HER2 gene mutation, for which there was previously no targeted therapy for lung cancer patients.
  • Since joining a clinical trial and taking a daily tablet, her tumour has shrunk, and she has not needed further chemotherapy.

Susan Gasson, a 75-year-old from Greenwich, south-east London, is participating in a clinical trial for lung cancer. She was diagnosed with lung cancer in October 2020, marking her fourth cancer diagnosis in 40 years, having previously been treated for breast, cervical, and thyroid cancer.

Ms Gasson has a HER2 gene mutation, which can cause cells to grow and divide excessively. The Royal Marsden NHS Foundation Trust, where she has received most of her treatment, stated that before this trial, there was no targeted therapy for lung cancer patients with this specific mutation.

Since starting the trial, Ms Gasson's tumour has shrunk, and she has not required further chemotherapy. She now has a CT scan every six weeks and reports minimal side effects, leading to a better quality of life.

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