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New £2.3m study trials personalised pain management for endometriosis

A new UK-wide study, funded by the National Institute for Health and Care Research (NIHR), will investigate if a personalised pain management plan can improve the quality of life for women with endometriosis.

  • The five-year study, led by the University of Aberdeen and NHS Grampian, will involve a 12-week personalised programme.
  • The programme includes cognitive behavioural therapy-informed psychotherapy, specialist physiotherapy, and medication guidance.
  • The trial aims to assess whether this strategy offers more effective treatment for women whose pain is not adequately controlled by surgery or medication.

Preparatory work has begun for a new £2.3 million UK-wide study investigating a personalised pain management programme for endometriosis. The five-year study, funded by the National Institute for Health and Care Research (NIHR), is led by the University of Aberdeen and NHS Grampian.

The trial will evaluate whether a personalised endometriosis-specific pain management programme (e-PMP) can offer more effective treatment for women whose pain is not adequately controlled by surgery or medication. The 12-week programme for participants will include pain medication alongside treatments such as physiotherapy, cognitive behavioural therapy-informed psychotherapy, and guidance on relationships, intimacy, and communication.

Pre-menopausal women will either receive the new programme alongside existing standard care or existing standard care alone, with the results then compared. Consultant gynaecologist Dr Lucky Saraswat, who is heading the study, stated that many women continue to suffer even after surgery or medication, and this study aims to understand if a tailored, interdisciplinary programme can offer long-term improvements in quality of life.

Why this matters: Endometriosis is a system-wide inflammatory disease that can cause debilitating pain, affecting relationships, work, education, and mental health, with no current cure.

What this means for you: If effective, this new personalised pain management programme could become a vital new treatment option for women with endometriosis, particularly for those who wish to avoid repeated surgery or hormonal therapies.

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