Crystal Palace manager Pierre Sage experienced a Europa League defeat as his team lost 3-2 to his former club, Lyon, at the Groupama Stadium. Corentin Tolisso opened the scoring for Lyon, with Ernest Nuamah doubling their lead in the first half.
Yéremy Pino reduced the deficit for Palace after the break, but Pavel Sulc restored Lyon's two-goal advantage. Daichi Kamada, a substitute for Palace, scored with nine minutes remaining, but the Eagles could not find an equaliser.
In other Europa League action, Milan achieved a 4-0 victory over Red Bull Salzburg, with Italian teenager Alphadjo Cissè scoring a hat-trick. Gonçalo Ramos added a fourth goal for Milan.
Bayer Leverkusen now lead the standings after a 4-0 win against Polish side Lech Poznan. Patrik Schick scored twice from the penalty spot, and Malik Tillman and Ibrahim Maza also found the net.