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US opioid overdose deaths fall to 70,000 in 2025, but crisis continues

The number of people dying from drug overdoses in the United States, mostly from opioids, decreased to around 70,000 last year, down from 110,000 in 2022.

  • Around 70,000 people in the US died from drug overdoses, mostly opioids, in 2025.
  • This figure is a decrease from 110,000 overdose deaths recorded in 2022.
  • Synthetic opioids are described as more powerful and readily available, altering the drug landscape.

The number of drug overdose deaths in the United States, predominantly from opioids, has seen a reduction, falling to approximately 70,000 last year. This figure is a decrease from the 110,000 overdose deaths recorded in 2022.

Despite the drop in fatalities, the opioid crisis is not considered over. Synthetic opioids are noted for being more potent and widely available, which has changed the nature of drug use.

Karen, a former heroin user who is now a recovery worker, highlighted the increased danger of currently used drugs. She has been free from hard drugs for 17 years.

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